IV INDUCTION AGENTS

for all drugs we will discuss their chemistry , mechanism of action , pharmacodynamics , dosage , pharmacokinetics , clinical uses , side effects , contraindication .

iv anesthetics used for induction of anesthesia are llipophilic and preferentially partion into highly perfused lipid rich tissues ( brain , spinal cord ) , which accounts for their rapid onset of action

regardless of extent and speed of their metabolism , termination of the effect of a single bolus dose is result of redistribution of the drug into less perfused tissues such as skeletal muscles and fat